Maintaining Elastogenicity of Mesenchymal Stem Cell-Derived Smooth Muscle Cells in Two-Dimensional Culture.

Maintaining Elastogenicity of Mesenchymal Stem Cell-Derived Smooth Muscle Cells in Two-Dimensional Culture.

Abdominal aortic aneurysms (AAAs) are localized expansions of the stomach aorta that develop slowly to rupture. AAA progress is pushed by irreversible elastic matrix breakdown in the aorta wall by chronically upregulated matrix metalloproteases (MMPs). Since grownup vascular easy muscle cells (SMCs) poorly regenerate elastic matrix, we beforehand explored utility of bone marrow mesenchymal stem …

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