Influence of Bacterial Culture Medium on Peptidoglycan Binding of Cell Wall Lytic Enzymes

Influence of Bacterial Culture Medium on Peptidoglycan Binding of Cell Wall Lytic Enzymes

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The bacteriolysin lysostaphin (Lst) and endolysin PlyPH are potent modular lytic enzymes with exercise in opposition to clinically-relevant Gram-positive Staphylococcus aureus and Bacillus cereus, respectively. Both enzymes possess an N-terminal catalytic area and C-terminal binding area, with the latter conferring important enzyme specificity. Lst and PlyPH present diminished exercise within the presence of bacterial growth-supporting […]

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